Spyre Therapeutics

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About SYRE

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. Its product, Pegzilarginase, is in a Phase 3 pivotal trial for the treatment of Arginase 1 Deficiency. 

CEO
Cameron Turtle
CEOCameron Turtle
Employees
102
Employees102
Headquarters
Waltham, Massachusetts
HeadquartersWaltham, Massachusetts
Founded
2013
Founded2013
Employees
102
Employees102

SYRE Key Statistics

Market cap
7.39B
Market cap7.39B
Price-Earnings ratio
-36.74
Price-Earnings ratio-36.74
Dividend yield
—
Dividend yield—
Average volume
1.74M
Average volume1.74M
High today
$80.88
High today$80.88
Low today
$77.50
Low today$77.50
Open price
$78.15
Open price$78.15
Volume
1.15M
Volume1.15M
52 Week high
$110.18
52 Week high$110.18
52 Week low
$21.15
52 Week low$21.15

Stock Snapshot

As of today, Spyre Therapeutics(SYRE) shares are valued at $80.10. The company's market cap stands at 7.39B, with a P/E ratio of -36.74.

During the trading session on 2026-10-16, Spyre Therapeutics(SYRE) shares reached a daily high of $80.88 and a low of $77.50. At a current price of $80.10, the stock is +3.4% higher than the low and still -1.0% under the high.

Trading activity shows a volume of 1.15M, compared to an average daily volume of 1.74M.

The stock's 52-week range extends from a low of $21.15 to a high of $110.18.

The stock's 52-week range extends from a low of $21.15 to a high of $110.18.

Analyst ratings

94%

of 16 ratings
Buy
93.8%
Hold
6.3%
Sell
0%

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