SPDR S&P Biotech ETF

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About XBI

XBI tracks an equal-weighted index of US biotechnology stocks. 

Index-Tracked
S&P 500 TR USD
Index-TrackedS&P 500 TR USD
Category
Health
CategoryHealth
Number of holdings
128
Number of holdings128
Inception Date
Jan 31, 2006
Inception DateJan 31, 2006

What's in this fund

Sectors

As of September 2, 2025
Healthcare100.00%

Top 10 Holdings (28.30% of total assets)

As of September 2, 2025
NameSymbol% Assets
Alnylam PharmaceuticalsALNY3.37%
Insmed IncorporatedINSM3.33%
United TherapeuticsUTHR3.30%
Halozyme TherapeuticsHALO3.06%
IncyteINCY2.81%
NeurocrineNBIX2.57%
RegeneronREGN2.50%
Madrigal PharmaceuticalsMDGL2.51%
AbbVieABBV2.49%
BiogenBIIB2.36%

XBI Key Statistics

AUM
5.39B
AUM5.39B
Price-Earnings ratio
-31.55
Price-Earnings ratio-31.55
30-Day yield
0.07
30-Day yield0.07
Average volume
7.99M
Average volume7.99M
High today
$95.56
High today$95.56
Low today
$93.70
Low today$93.70
Open price
$93.81
Open price$93.81
Volume
9.16M
Volume9.16M
52 Week high
$105.47
52 Week high$105.47
52 Week low
$66.66
52 Week low$66.66
Expense ratio
0.35
Expense ratio0.35
View Prospectus and Reports

Average Annual Return

All investments involve risks, including the loss of principal. Performance data represents past performance and is no guarantee of future results. Investment returns and principal value will fluctuate and are subject to market volatility. An investment, when redeemed, may be worth more or less than the original cost. Current performance may be lower or higher than the performance data quoted.