SPDR S&P Biotech ETF

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About XBI

XBI tracks an equal-weighted index of US biotechnology stocks. 

Index-Tracked
S&P 500 TR USD
Index-TrackedS&P 500 TR USD
Category
Health
CategoryHealth
Number of holdings
135
Number of holdings135
Inception Date
Jan 31, 2006
Inception DateJan 31, 2006

What's in this fund

Sectors

As of October 20, 2025
Healthcare100.00%

Top 10 Holdings (19.16% of total assets)

As of October 20, 2025
NameSymbol% Assets
CRISPRCRSP2.35%
Revolution MedicinesRVMD1.99%
Insmed IncorporatedINSM1.91%
Ionis PharmaceuticalsIONS1.90%
Exact SciencesEXAS1.89%
ModernaMRNA1.86%
NateraNTRA1.84%
AbbVieABBV1.81%
United TherapeuticsUTHR1.81%
AmgenAMGN1.80%

XBI Key Statistics

AUM
6.58B
AUM6.58B
Price-Earnings ratio
-26.41
Price-Earnings ratio-26.41
30-Day yield
-0.03
30-Day yield-0.03
Average volume
10.69M
Average volume10.69M
High today
$107.88
High today$107.88
Low today
$106.50
Low today$106.50
Open price
$107.38
Open price$107.38
Volume
6.34M
Volume6.34M
52 Week high
$110.96
52 Week high$110.96
52 Week low
$66.66
52 Week low$66.66
Expense ratio
0.35
Expense ratio0.35
View Prospectus and Reports

Average Annual Return

All investments involve risks, including the loss of principal. Performance data represents past performance and is no guarantee of future results. Investment returns and principal value will fluctuate and are subject to market volatility. An investment, when redeemed, may be worth more or less than the original cost. Current performance may be lower or higher than the performance data quoted.