ALPS Medical Breakthroughs ETF

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About SBIO

SBIO tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. 

CEO
CEO
Employees
—
Employees—
Headquarters
Headquarters
Founded
2007
Founded2007
Employees
—
Employees—

What's in this fund

Sectors

As of October 16, 2025
Healthcare100.00%

Top 10 Holdings (30.04% of total assets)

As of October 16, 2025
NameSymbol% Assets
Rhythm PharmaceuticalsRYTM3.68%
Avidity BiosciencesRNA3.44%
MerusMRUS3.36%
CytokineticsCYTK3.34%
Axsome TherapeuticsAXSM3.05%
NuvalentNUVL2.80%
VaxcytePCVX2.66%
Metsera, Inc.MTSR2.65%
Arrowhead PharmaceuticalsARWR2.54%
Krystal BiotechKRYS2.52%

SBIO Key Statistics

AUM
96.20M
AUM96.20M
Price-Earnings ratio
-17.55
Price-Earnings ratio-17.55
30-Day yield
-0.46
30-Day yield-0.46
Average volume
39.63K
Average volume39.63K
High today
$42.38
High today$42.38
Low today
$41.76
Low today$41.76
Open price
$41.92
Open price$41.92
Volume
10.76K
Volume10.76K
52 Week high
$43.60
52 Week high$43.60
52 Week low
$22.33
52 Week low$22.33
Expense ratio
0.50
Expense ratio0.50
View Prospectus and Reports

Average Annual Return

All investments involve risks, including the loss of principal. Performance data represents past performance and is no guarantee of future results. Investment returns and principal value will fluctuate and are subject to market volatility. An investment, when redeemed, may be worth more or less than the original cost. Current performance may be lower or higher than the performance data quoted.