Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. Its product, Pegzilarginase, is in a Phase 3 pivotal trial for the treatment of Arginase 1 Deficiency. The company was founded by George Georgiou and David G. Lowe on December 16, 2013 and is headquartered in Waltham, MA.

All investments involve risks, including the loss of principal. Securities trading offered through Robinhood Financial LLC, Member SIPC and a registered broker-dealer. Full disclosure

All investments involve risks, including the loss of principal. Securities trading offered through Robinhood Financial LLC, [Member SIPC ](https://www.sipc.org/) and a registered broker-dealer.

All investments involve risks, including the loss of principal. Past performance is no guarantee of future results. The provision of this information does not constitute investment advice or a recommendation of any security, transaction, account type, investment strategy involving securities, or order. Securities trading offered through Robinhood Financial LLC, [Member SIPC](https://www.sipc.org/), a registered broker-dealer, and a subsidiary of Robinhood Markets, Inc.

Options trading entails significant risk and is not appropriate for all investors. Options transactions are often complex and may involve the potential of losing your entire investment. Investors should consider their investment objectives and risks carefully before investing in options. To learn more about the risks associated with options, please read the [Characteristics and Risks of Standardized Options](https://cdn.robinhood.com/assets/robinhood/legal/Characteristics%20and%20Risks%20of%20Standardized%20Options.pdf) before you begin trading options. Supporting documentation for any claims, if applicable, will be furnished upon request.

Please also be aware of the risks listed in the following documents: [Day Trading Risk](https://d2ue93q3u507c2.cloudfront.net/assets/robinhood/legal/RHF%20Day%20Trading%20Risk%20Disclosure.pdf) [Disclosure Statement](https://d2ue93q3u507c2.cloudfront.net/assets/robinhood/legal/RHF%20Day%20Trading%20Risk%20Disclosure.pdf) and [FINRA Investor Information](https://www.finra.org/investors/learn-to-invest/advanced-investing/purchasing-margin).

Commission-free trading refers to $0 commissions for Robinhood Financial self-directed individual cash or margin brokerage accounts that trade U.S. listed securities and certain OTC securities electronically. Keep in mind, other fees such as trading (non-commission) fees, Gold subscription fees, wire transfer fees, and paper statement fees may apply to your brokerage account. Please see Robinhood Financial’s [fee schedule](https://cdn.robinhood.com/assets/robinhood/legal/RHF%20Fee%20Schedule.pdf) to learn more.

The line chart allows you to select different time spans. Each time span plots a time interval. On the 1 day span and weekly span, there is additional logic to only show the interval when trades occur. This allows you to see when trading volume occurs during periods of slower activity like extended hours or thinly traded equities. The candlestick chart works in the same manner.

Charts for 24 Hour Market securities display activity from 12 - 12 localized time. The “High” and “Low” statistics represent the highest and lowest values from 12 AM - 12 AM localized time. This includes market, extended, and overnight hours. Overnight volume displays the number of shares that are traded on the BOATS ATS during overnight hours, from 8 PM - 4 AM ET.

There are additional, unique risks with trading outside of regular market hours you should be aware of before making an investment decision, including the risk of lower liquidity, increased volatility, greater spreads, and pricing uncertainty. Please review the [Extended Hours Trading Disclosure](https://cdn.robinhood.com/assets/robinhood/legal/ExtendedHoursTradingDisclosure.pdf) for more information concerning these risks.

The People Also Own feature is provided for informational purposes only and is not a recommendation to buy, hold, or sell any security. Robinhood uses a proprietary statistical model to predict the securities that are most likely to be held by other Robinhood users that hold the security displayed. The model looks for correlation among sufficiently large portfolios and controls for the fact that some securities are broadly held in general. The feature is not customized per user. The data is generally updated daily.

Certain fundamental, market data, or other information is provided by FactSet Research Systems, Inc. (Copyright © 2021 FactSet Research Systems Inc. All rights reserved.), by Xignite (xignite.com), OTC Markets Group, ICE Data Services, and/or other third party providers. Realtime quote and/or trade prices are not sourced from all markets. Robinhood does not make any express or implied warranty or guarantee relating to the accuracy, timeliness or completeness of any third-party information.  

The Analyst Ratings feature, including the percentages of Buy, Hold, and Sell ratings and any price targets or other third party analyst information, collects information from third-party sources and is for informational purposes only. It is not intended to serve as a recommendation to a customer to buy, hold or sell any security in their self-directed Robinhood account, or any other account. ”Buy” aggregates both “Buy” and “Overweight” ratings from third party analysts, “Hold” aggregates “Hold” ratings from third party analysts, and “Sell” aggregates both “Sell” and “Underweight” ratings from third party analysts. Analyst ratings and related content is provided by third party market data providers. Robinhood does not guarantee the accuracy, timeliness or completeness of any third-party information.

Information provided by Morningstar or contained under the “Bulls Say” and “Bears Say” headings: (1) is proprietary to Morningstar Research Services LLC, Morningstar, Inc. and/or their content providers; (2) may not be copied or distributed; and (3) is not warranted to be accurate, complete or timely. Neither Morningstar Research Services, Morningstar nor their content providers are responsible for any damages or losses arising from any use of this information. Access to or use of the information contained herein does not establish an advisory or fiduciary relationship with Morningstar Research Services, Morningstar, Inc. or their content providers. Past performance is no guarantee of future results. ©2021 Morningstar. All Rights Reserved. Robinhood does not guarantee the accuracy, timeliness or completeness of any third-party information.

Lists may be generated using a combination of data from Morningstar Research Services, LLC, Morningstar, Inc. and/or FactSet Research Systems Inc. and/or their content providers and public filing information from the U.S. Securities and Exchange Commission EDGAR database. Information may not be current. ©2021 Morningstar.  © 2021 FactSet Research Systems Inc. All Rights Reserved. Lists are provided for informational purposes only by Robinhood Markets, Inc., and are not investment advice or a recommendation to buy, hold, or sell any security. Robinhood Lists are not personalized recommendations, and the securities listed may not be suitable for you. You should not buy or sell any security on a Robinhood List without first determining it is appropriate for your portfolio or investment strategy. 

All information (the “ICE Data Information”) provided by ICE Data Connectivity & Feeds, Inc. (together with its affiliates, collectively referred to as “ICE Data”) is owned by or licensed to ICE Data and any user is permitted to use such Information only for such user’s personal use. In no event shall any user publish, retransmit, redistribute or otherwise reproduce any ICE Data Information in any format to anyone, and no user shall use any ICE Data Information in or in connection with any business or commercial enterprise, including, without limitation, any securities, investment, accounting, banking, legal or media business or enterprise.  Prior to relying on any ICE Data Information and/or the execution of a security trade based upon such Information, you are advised to consult with your broker or other financial representative to verify pricing information. The ICE Data Information is provided to the users “as is”. Neither ICE Data, nor any third party data provider, make any express or implied warranties of any kind regarding the ICE Data Information, including, without limitation, any warranty of merchantability or fitness for a particular purpose or use. Neither ICE Data, nor any third party data provider, will be liable to any user or anyone else for any interruption, inaccuracy, error or omission, regardless of cause, in the ICE Data Information or for any damages (whether direct or indirect, consequential, punitive or exemplary) resulting therefrom.

Certain Information may be provided directly or indirectly by OTC Markets Group Inc. or its affiliates (“OTC Markets Group Data”). You are not permitted to reproduce, duplicate, copy, sell, trade, resell or exploit for any commercial purpose, any part of, the use of, or access to, OTC Markets Group Data. OTC Markets Group Data is provided “as is,” and there are no warranties of any kind, express, implied or statutory (including, without limitation, timeliness, truthfulness, sequence, completeness, accuracy, freedom from interruption, any implied warranties arising from trade usage, course of dealing, or course of performance, or the implied warranties of merchantability or fitness for a particular purpose).


Aeglea BioTherapeutics

Why Robinhood?

About AGLE

AGLE Key Statistics