Spyre Therapeutics

1D
1W
1M
3M
YTD
1Y
5Y
ALL

Why Robinhood?

Robinhood gives you the tools you need to put your money in motion. You can buy or sell SYRE and other ETFs, options, and stocks.

About SYRE

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. Its product, Pegzilarginase, is in a Phase 3 pivotal trial for the treatment of Arginase 1 Deficiency. 

CEO
Cameron Turtle
CEOCameron Turtle
Employees
102
Employees102
Headquarters
Waltham, Massachusetts
HeadquartersWaltham, Massachusetts
Founded
2013
Founded2013
Employees
102
Employees102

SYRE Key Statistics

Market cap
3.96B
Market cap3.96B
Price-Earnings ratio
-24.27
Price-Earnings ratio-24.27
Dividend yield
Dividend yield
Average volume
893.07K
Average volume893.07K
High today
$54.96
High today$54.96
Low today
$46.28
Low today$46.28
Open price
$46.28
Open price$46.28
Volume
1.04M
Volume1.04M
52 Week high
$54.96
52 Week high$54.96
52 Week low
$10.91
52 Week low$10.91

Stock Snapshot

As of today, Spyre Therapeutics(SYRE) shares are valued at $54.96. The company's market cap stands at 3.96B, with a P/E ratio of -24.27.

During the trading session on 2026-03-31, Spyre Therapeutics(SYRE) shares reached a daily high of $54.96 and a low of $46.28. At a current price of $54.96, the stock is +18.8% higher than the low and still 0.0% under the high.

Trading volume for Spyre Therapeutics(SYRE) stock has reached 1.04M, versus its average volume of 893.07K.

Over the past 52 weeks, Spyre Therapeutics(SYRE) stock has traded between a high of $54.96 and a low of $10.91.

Over the past 52 weeks, Spyre Therapeutics(SYRE) stock has traded between a high of $54.96 and a low of $10.91.

Analyst ratings

100%

of 15 ratings
Buy
100%
Hold
0%
Sell
0%

People also own

Based on the portfolios of people who own SYRE. This list is generated using Robinhood data, and it’s not a recommendation.

Similar Marketcap

This list is generated by looking at the six larger and six smaller companies by market cap in relation to this company.

Popular Stocks

This list is generated by looking at the top 100 stocks and ETFs most commonly held by Robinhood customers and showing a random subset

Newly Listed

This list is generated by showing companies that recently went public.

All investments involve risks, including the loss of principal. Securities trading offered through Robinhood Financial LLC, Member SIPC and a registered broker-dealer. Options are risky and aren’t suitable for all investors. To learn more about risks, read the Options Disclosure Document.